ArticleEJHaem2026
Global Burden of Sickle Cell Disease: Adequacy of Pain Control as Evidenced by Frequency of Oral Pain Medication Use, Health Outcomes, and Emotional Well-Being Across Diverse Populations.
Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Introduction: Sickle cell disease (SCD) is a chronic genetic disorder causing severe pain, anemia, and systemic complications that negatively affect patients' physical and mental well-being. The aim of this global cross-sectional study was to evaluate the relationship between oral pain medication (OPM) use frequency and health outcomes, emotional well-being, social participation, and satisfaction with care among people with SCD. Method: Data were collected via an online survey across five continents from February to September 2024. Results: A total of 123 participants were divided into two groups based on OPM use frequency: weekly or more ( Conclusion: These findings suggest that higher OPM use is associated with poorer physical, emotional, and social outcomes. The results highlight the importance of comprehensive and multidisciplinary care approaches that may support the overall well-being of individuals with SCD and utilize OPM as a relevant clinical metric to assess disease burden in SCD. Clinical Trial: The authors have confirmed clinical trial registration is not needed for this submission.
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