ArticleFrontiers in nutrition2026
Association between Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in centenarians, with a focus on nonlinear and threshold effects: a multi-method observational study.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The Geriatric Nutritional Risk Index (GNRI) is a simple index for assessing nutritional status in older adults. Its association with mortality has been shown in general elderly populations, but data in centenarians are scarce. We aimed to examine the relationship between GNRI and all-cause mortality in centenarians. Methods: We included 1,002 centenarians with complete clinical and follow-up data and categorized them into quartiles according to GNRI. All-cause mortality was the primary endpoint. Cox proportional hazards models, restricted cubic splines, subgroup analyses and sensitivity analyses were used to evaluate the association between GNRI and mortality. To enhance robustness, propensity score matching (PSM) was performed. Results: Among the 1,002 centenarians (18% male), the overall mortality rate was 92.7%. In multivariable Cox models, GNRI was inversely associated with mortality (per 1-unit increase: HR 0.97, 95% CI 0.96-0.98, Conclusion: GNRI is strongly and nonlinearly associated with all-cause mortality in centenarians, with a key threshold around 96. This threshold may provide a quantitative target for individualized nutritional assessment and intervention in this extremely old population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.