ArticleFrontiers in neurology
Correlation between blood pressure variability and prognosis of endovascular therapy in ischemic stroke due to middle cerebral artery occlusion.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Purpose: To evaluate the impact of post-endovascular therapy (EVT) systolic, diastolic, and pulse pressure (PP) variability on 3 month functional outcomes in patients with middle cerebral artery occlusion. Methods: Patients were classified as having good (mRS 0-2) or poor (mRS 3-6) 90 day outcomes. We compared 48 h postoperative BP parameters and BPV indices (SD, CV, and ARV). Multivariable logistic regression adjusted for age, baseline NIHSS, hypertension, atrial fibrillation, and pre-stroke mRS was used to examine associations between BPV and outcome. Results: The average real variability of systolic blood pressure (SBPARV: 10.08 vs. 7.89, Conclusion: In this retrospective cohort, higher postoperative SBP ARV and PP ARV were independently associated with poor 90 day functional outcome after EVT; however, given the small sample size and observational design, the predictive value of BPV parameters is likely limited. BPV may be an epiphenomenon of more severe stroke rather than a causal determinant or clinically actionable target.
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