Evidence map›Paper›PMID 41798717›Full record

ArticleEndocrines2023

Obesity Is Associated with Increased F

Mohammad Saleem, Paul D Kastner, Pouya Mehr, Ginger L Milne, Jeanne A Ishimwe, Jennifer H Park, Cyndya A Shibao, Annet Kirabo

Abstract read
In one paragraph

Article in Endocrines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Open veterinary journal · 2025
    Article
  2. Article
  3. Complete autonomic blockade reveals nitric oxide contribution to blood pressure regulation in obese Black women.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammad SaleemDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.ORCID 0000-0001-8091-8361
Paul D KastnerDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.
Pouya MehrDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.
Ginger L MilneDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.ORCID 0000-0003-3890-151X
Jeanne A IshimweDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.
Jennifer H ParkDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.
Cyndya A ShibaoDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.
Annet KiraboDepartment of Medicine, Division of Clinical Pharmacology, Room 536 Robinson Research Building, Vanderbilt University Medical Center, Nashville, TN 37212-8802, USA.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
Mechanisms of Immune Activation in HypertensionR35HL140016 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRISON, DAVID G · 2018 to 2024
$5.3M
ENaC regulation and its role in blood pressure homeostasisR01HL147818 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Annet Kirabo, Thomas R Kleyman · 2019 to 2026
$4.6M
Enhancing parasympathetic activity to reduce vascular oxidative stress and endothelial dysfunctionR01HL157584 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET, SHIBAO, CYNDYA ADRIANA · 2021 to 2024
$3.0M
Immune Mechanisms of Salt-Sensitive hypertensionR01HL144941 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2021 to 2025
$3.0M
Deep phenotypic and functional characterization of salt-responsive immune cells in human salt senstive hypertension using CTE-seqR03HL155041 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2021 to 2022
$173k
NCATS NIH HHS UL1 TR002243NHLBI NIH HHS R01 HL144941NHLBI NIH HHS R01 HL147818NHLBI NIH HHS R01 HL157584NHLBI NIH HHS R03 HL155041NHLBI NIH HHS R35 HL140016NIDDK NIH HHS P30 DK020593
6 · The paper itself

Abstract

Obesity affects over 40% of the adult population and is a major risk factor for morbidity and mortality due to cardiovascular disease. Black women have one of the highest prevalences of obesity, insulin resistance, hypertension, and cardiovascular events in the US. We previously found that free radical-mediated lipid peroxidation contributes to IL-6 production in dendritic cells leading to inflammation and hypertension. Thus, we hypothesized that F

Indexed as

black womenF2-isoprostanesinflammationlipid oxidationobesityoxidative stress

Identifiers

PMID41798717
PMCPMC12965753

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.