Evidence map›Paper›PMID 41798687›Full record

ArticleBioMed research international2026

Diabetes Mellitus Accelerates Alzheimer's Disease Development by Affecting the Gut Microbiome.

Qiong He, Zixiao Zhao, Donglang Jiang, Aihua Fei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiong HeDepartment of General Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China, xinhuamed.com.cn.ORCID https://orcid.org/0000-0001-5766-5677
Zixiao ZhaoState Key Laboratory of Vaccines for Infectious Disease, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, China, xmu.edu.cn.
Donglang JiangDepartment of Nuclear Medicine& PET Center, Huashan Hospital, Fudan University, Shanghai, China, fudan.edu.cn.ORCID https://orcid.org/0000-0002-3787-3847
Aihua FeiDepartment of General Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China, xinhuamed.com.cn.ORCID https://orcid.org/0000-0002-6726-4145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence suggests a link between Alzheimer's disease (AD) and diabetes mellitus (DM). However, the precise mechanisms by which DM contributes to AD remain unclear. This study is aimed at elucidating the potential role of DM in the early stages of AD. Accordingly, a streptozotocin (STZ)-induced diabetic 5 × familial AD (FAD) mouse model was established. Immunohistochemistry and positron emission tomography/computed tomography (PET/CT) scanning were performed to examine amyloid beta (A

Indexed as

Alzheimer DiseaseDiabetes Mellitus, ExperimentalGastrointestinal MicrobiomeAmyloid beta-PeptidesAnimalsBrainButyratesDisease Models, AnimalHumansMaleMicePositron Emission Tomography Computed TomographyAmyloid beta-PeptidesButyratesAlzheimer′s diseasediabetes mellitusgut microbesshort-chain fatty acids

Identifiers

PMID41798687
PMCPMC12964169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.