ArticleChemical science2026
Lipid-donor-anchored genome mining uncovers dioxanopeptins, antibacterial lipopeptides with a 1,3-dioxane functionalized polyunsaturated lipid tail.
Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Non-ribosomal lipopeptide antibiotics derive much of their antibacterial performance from the structure of their lipid tail, yet genome mining remains largely peptide-centric and rarely prioritizes lipid donor formation as an entry point. Herein, we establish a lipid-donor-anchored discovery strategy using
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