Evidence map›Paper›PMID 41798590›Full record

ArticleSurgical case reports2026

A Rare Case of Mucinous Carcinoma Arising in Association with an Intraductal Papilloma.

Haruka Yamasaki, Sayaka Kuba, Momoko Akashi, Michi Morita, Aki Yukutake, Yuki Hara, Aya Tanaka, Hajime Imamura, Ryota Otsubo, Megumi Matsumoto and 4 more

Abstract readCase Reports
In one paragraph

Article in Surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Haruka YamasakiDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Sayaka KubaDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Momoko AkashiDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Michi MoritaDepartment of Breast and Endocrine Surgery, National Hospital Organization Nagasaki Medical Center, Omura, Nagasaki, Japan.
Aki YukutakeDepartment of Breast and Endocrine Surgery, Nagasaki Harbor Medical Center, Nagasaki, Nagasaki, Japan.
Yuki HaraDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Aya TanakaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Hajime ImamuraDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Ryota OtsuboDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Megumi MatsumotoDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Kengo KanetakaDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Keitaro MatsumotoDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Susumu EguchiDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Rin YamaguchiDepartment of Breast Center/Diagnostic Pathology, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntraductal papilloma (IDP) is a benign breast lesion that accounts for 3%-6% of core biopsy diagnoses. It is considered a high-risk precursor due to its association with atypia, ductal carcinoma in situ, and invasive carcinoma. Although IDP-NOS (not otherwise specified) rarely progresses to invasive cancer, IDP with atypia carries a higher risk of malignant transformation. CASE PRESENTATION: A 57-year-old woman presented with a mass in the left breast. Mammography revealed a microlobulated mass, and ultrasonography showed a well-defined, coarse isoechoic mass measuring 26 mm with a disrupted anterior border. MRI revealed a high T2 signal outside the center of the tumor, with early enhancement and a plateau phase. Based on these imaging findings, mucinous carcinoma was suspected; a core needle biopsy revealed both mucinous carcinoma and ductal carcinoma with a mucocele-like lesion. The patient subsequently underwent a total mastectomy and sentinel lymph node biopsy for cT2N0 breast cancer. The surgical specimen revealed a mucinous carcinoma spreading around the papilloma, with a distinct transition zone from papilloma to mucinous carcinoma.

conclusionsThis case suggests that mucinous carcinoma may arise from an intraductal papilloma, emphasizing the importance of appropriate clinical follow-up.

Indexed as

breast cancerintraductal papillomamucinous carcinomatransition zone

Identifiers

PMID41798590
PMCPMC12962787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.