ArticleCureus2026
Underrecognized Thrombotic Risk in Klinefelter Syndrome: A Clinical Insight.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Sex differences in endothelial cell biology: cellular phenotypes and molecular regulators.Frontiers in physiology · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Klinefelter syndrome (KS), the most common male aneuploidy (47,XXY), is linked to hypogonadism, gynecomastia, and infertility, with an established but underrecognized association with venous thromboembolism and limited data on mechanisms in patients without additional thrombophilic conditions. We report the case of a 33-year-old South Asian male with subacute-to-chronic deep vein thrombosis (DVT) of the right leg and absent traditional thrombosis risk factors. Clinical evaluation, hormonal assays, and karyotyping confirmed KS. Extensive investigations ruled out congenital and acquired thrombophilias. The patient responded well to anticoagulation therapy, achieving symptom resolution. This case highlights the need for awareness of thrombotic risks in KS and underscores the importance of further research into the underlying mechanisms of this association.
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Registered trials
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