ArticleCureus2026
Purulent Pericarditis With Cardiac Tamponade Triggered by Left-Sided Infective Endocarditis in Active Systemic Lupus Erythematosus: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Systemic lupus erythematosus (SLE)-associated pericardial effusion is generally sterile, and purulent pericarditis is rare; however, delayed recognition can be fatal. In active SLE, immunologic abnormalities - such as hypocomplementemia and impaired neutrophil function - together with concurrent immunosuppressive therapy, may predispose patients to invasive infections. We report a rare clinical course in which left-sided infective endocarditis in a patient with active SLE progressed to purulent pericarditis and cardiac tamponade, underscoring the need for rapid diagnostic consideration and timely intervention. A 32-year-old woman presented with fever, dyspnea, and rapidly progressive shock. Imaging revealed massive circumferential pericardial effusion with cardiac compression. After obtaining blood cultures, empiric intravenous antimicrobial therapy was initiated, and fluoroscopy-guided pericardial drainage yielded a large volume of brownish, purulent-appearing effluent. Transthoracic echocardiography demonstrated vegetation and perforation of the anterior mitral leaflet with mitral regurgitation. Blood cultures grew methicillin-susceptible
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