ArticleCureus2026
Lichen Planus Pigmentosus Localized to the Glans Penis: A Rare Presentation Treated With Ruxolitinib.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of JAK Inhibitors in Lichen Planus: A Systematic Review of the Available Clinical Evidence.Mediators of inflammation · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lichen planus pigmentosus (LPP) is a rare variant of lichen planus characterized by macules of black or dark brown color distributed in the sun-exposed areas of the body. It is common among individuals with darker skin, with cases reported in the Middle East, Korea, Japan, and Latin America. Genital involvement is rare, with no reported cases describing isolated penile disease. Management of genital LPP is also challenging due to the sensitive nature of the skin and the associated risks of long-term topical corticosteroid use. We report a case of a 24-year-old male presenting with asymptomatic hyperpigmented lesions localized to the dorsal penile shaft, diagnosed as LPP on histopathology. The patient demonstrated minimal response to prior therapies, including topical corticosteroids and topical calcineurin inhibitors (TCIs). Given treatment resistance, topical ruxolitinib was initiated, with subtle improvement. This case highlights a rare anatomic presentation of LPP and explores the potential role of topical JAK inhibitors as a novel therapeutic option for lichen-planus-associated pigmentary disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.