Evidence map›Paper›PMID 41798325›Full record

ArticleBJA open2026

Association of the dose of maternal general anaesthesia during Caesarean delivery with 5-minute Apgar scores: a retrospective single centre cohort study.

Shubhangi Singh, Thomas T Klumpner, Baskar Rajala, Jefferine Li, Monica Servin, Robert Schumacher, Alissa Carver, Carlo Pancaro, Nicole Barrios, Yuan Yuan and 2 more

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In one paragraph

Article in BJA open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shubhangi SinghDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Thomas T KlumpnerDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Baskar RajalaDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Jefferine LiDepartment of Anesthesiology, University of California, Irvine, CA, USA.
Monica ServinAmbulatory Anesthesia Solutions, Novi, MI, USA.
Robert SchumacherDepartment of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Alissa CarverWilmington Maternal-Fetal Medicine, Wilmington, NC, USA.
Carlo PancaroDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Nicole BarriosDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Yuan YuanDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Graciela MentzDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Joanna A KountanisDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neuraxial anaesthesia is preferred for Caesarean deliveries, but general anaesthesia is used in situations such as emergencies, contraindications to neuraxial anaesthesia, or anticipated complex deliveries. Although previous research has examined how the Methods: This retrospective single centre cohort study evaluated the association between total maternal general anaesthesia dose and 5-min Apgar scores among neonates born Results: Analysis included 101 neonates born via planned Caesarean delivery under maternal general anaesthesia. Every 5-MAC-minute increase in EMAC-AUC was associated with a 10% increase in the adjusted odds of a 5-min Apgar score of <7 (odds ratio, 1.10; 95% confidence interval, 1.05-1.22; Conclusions: In this cohort of preterm, late preterm, and term neonates delivered

Indexed as

Apgar scoresCaesarean deliveryCaesarean hysterectomygeneral anaesthesiamaternal general anaestheticneonatal outcomes

Identifiers

PMID41798325
PMCPMC12964278

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