ArticleJGH open : an open access journal of gastroenterology and hepatology2026
Factors Associated With Loss of Fecal Biomarker Accuracy During Routine Assessment of Inflammatory Bowel Disease.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Factors Associated With Loss of Fecal Biomarker Accuracy During Routine Assessment of Inflammatory Bowel Disease.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Fecal calprotectin (fCal) and fecal myeloperoxidase (fMPO) have been proposed as biomarkers for monitoring inflammatory bowel disease (IBD); however, their reliability is not fully established. This study investigated clinical variables associated with the loss of accuracy of fecal biomarkers. Methods: Post hoc analyses were performed on previously reported data (New indicators of disease activity in IBD (NIDA-IBD) cohort), which examined fecal biomarkers in individuals with IBD undergoing colonoscopy. Positive and negative results were recorded using previously identified thresholds (fCal, 150 μg/g; fMPO, 8 μg/g). Univariable logistic regression analyses were used to identify clinical variables (patient demographics, disease location and duration, symptoms and medication use) associated with false-positive and false-negative results. Subgroup analyses (Mann-Whitney Results: One hundred and seventy individuals from the NIDA-IBD cohort were included for analyses (CD, Conclusions: No clinical variables were found to be associated with loss of biomarker accuracy, including fecal myeloperoxidase at widely used thresholds. Fecal biomarkers improved prediction of disease activity.
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