ArticleNeuropsychiatric disease and treatment2026
Benzodiazepines Prescribed to Hospitalized Patients with Major Depressive Disorder: A 3-year Retrospective Observational Study.
Article in Neuropsychiatric disease and treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Major Depressive Disorder (MDD) has a relatively high prevalence in China, and its treatment often involves benzodiazepines. This study investigated the proportion and types of benzodiazepines prescribed to hospitalized patients with MDD, and assessed changes in prescribing patterns over a 3-year follow-up period. Methods: This retrospective study analyzed electronic health records of inpatients diagnosed with MDD at the Affiliated Kangning Hospital of Ningbo University from January 1 to December 30, 2020. Comprehensive data were collected, encompassing sociodemographic details and baseline clinical characteristics. A follow-up assessment was conducted three years later. Results: The present study ultimately included 278 inpatients with MDD. At baseline, 236 (84.9%) were prescribed benzodiazepines. At 3 years, 102 (36.7%) patients were prescribed benzodiazepines. Benzodiazepine use varied significantly over time ( Conclusion: Overall, our findings suggest that benzodiazepine prescriptions are highly prevalent among inpatients diagnosed with MDD. It is advisable to limit benzodiazepine prescriptions for MDD patients to within 12 months. Discontinuing benzodiazepines becomes more challenging after prolonged use beyond this period.
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