ArticleFrontiers in pediatrics2026
Screening of early predictive serum biomarkers and construction of a combined predictive model for refractory
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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5 authors.
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Abstract
Background: Methods: A total of 568 patients, including 130 RMPP cases and 438 GMPP cases, were enrolled. Clinical information, laboratory tests, and radiological features were compared. Univariate and multivariate logistic regression analyses identified serum biomarkers associated with RMPP. A combined predictive model using random forest approach was developed and externally validated. Results: RMPP patients showed significantly higher rates of older age, fever, tachypnea, chest tightness, wheezing, chills, extrapulmonary complications, decreased unilateral lung sounds, longer fever duration, hospital stay, antibiotic therapy, oxygenotherapy use, and Intensive Care Unit (ICU) admission (all Conclusions: Significant differences in clinical, laboratory, and radiological characteristics were observed between RMPP and GMPP. The combined multi-marker model shows strong potential for early risk identification of RMPP and may support timely clinical decision-making; however, prospective validation is needed before routine implementation.
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