ArticleFrontiers in pediatrics2026
The effect of purified hemoglobin spray on the treatment of pediatric patients with second-degree burns.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- A breath of fresh air: the role of oxygen carriers in plastic surgery.Frontiers in bioengineering and biotechnology · 2026Review
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1 author.
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Abstract
Introduction: Purified hemoglobin spray had emerged as a potential adjunctive therapy to accelerate wound healing in pediatric patients with burns. This retrospective study aimed to compare the healing process and post-treatment outcomes of children with second-degree burns treated with or without purified hemoglobin spray in a tertiary burn unit between December 1, 2023, and December 1, 2024. Data including demographics, burn characteristics (source, percentage, depth), number of dressings, length of hospital stay, and the day of complete epithelialization were recorded. Follow-up assessments at 3 and 6 months post-discharge evaluated the presence of pruritus and epithelialization defects, including hypertrophic scarring, pigmentation changes, or contractures. Methods: Data were collected from pediatric patients with second-degree burns treated in a tertiary burn unit between December 1, 2023, and December 1, 2024. Variables included demographics, burn characteristics (source, percent TBSA, depth), number of dressings, length of hospital stay, and day of complete epithelialization. Patients were grouped by receipt of 99.9% purified hemoglobin spray versus no spray. Follow-up assessments at 3 and 6 months post-discharge evaluated pruritus and epithelialization defects, including hypertrophic scarring, pigmentation changes, or contractures. Results: Patients treated with 99.9% purified hemoglobin spray had significantly shorter hospital stays and epithelialization times ( Discussion: These findings suggested that purified hemoglobin spray might enhance wound healing, reduce the need for frequent dressing changes, and minimize long-term complications in pediatric burn care.
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