ArticleFrontiers in pediatrics2026
Interim implementation and effectiveness results from the IMplementation of Physical Activity for Children and adolescents on Treatment (IMPACT) intervention and trial.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To support physical activity (PA) among pediatric cancer patients, the IMPACT (IMplementation of Physical Activity for Children and adolescents on Treatment) PA intervention was developed. IMPACT is a 1:1, supervised, PA intervention delivered by exercise professionals over videoconference. It is being evaluated in a hybrid effectiveness-implementation trial. This interim report: (1) examines implementation, (2) explores changes in select secondary effectiveness outcomes, and (3) reviews quality improvement data and documents refinements to date. Methods: Children and adolescents affected by cancer and blood disorders (5-18 years old), awaiting, on-, or <3 months off-treatment are referred or self-referred to the IMPACT intervention and trial. IMPACT is a 12-week, 1:1, supervised, PA intervention delivered by videoconference by a trained exercise professional. Interim IMPACT implementation covers Results: Between 1 March 2022 and 12 December 2024, 93 patients were referred (84 = healthcare provider referral; 9 = self-referred), 36 expressed interest, 14 consented and enrolled, and 12 completed the intervention (participation rate = 39%). Retention to the trial was 33%, adherence to PA sessions was 57%, no adverse events were reported, and missing data was 54%. Visual analysis of individual change scores suggests no significant changes in select secondary outcomes. Over 300 intervention and trial delivery hours were accrued, and intervention delivery fidelity was high (95.2 ± 3.83%). Data from quality improvement cycles informed refined and novel recruitment and outreach resources, including posters, brochures, videos, and presentations. Conclusions: Although levels of referral are high, participation, retention, and adherence rates are low. Results highlight critical areas for improvement to facilitate enrollment, improve adherence, and support data collection for the remaining months of intervention and trial delivery.
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