Evidence map›Paper›PMID 41798126›Full record

ArticleNeuro-oncology practice2026

The CARING intervention for neuro-oncology family caregivers: Primary outcomes from an abbreviated randomized controlled trial.

Maija Reblin, Steven K Sutton, Hyojin Choi, Deanna Witte, Kristen J Wells, Bradley J Zebrack, Peter Forsyth, Margaret M Byrne

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maija ReblinDepartment of Family Medicine, University of Vermont, Burlington, VT, USA.ORCID https://orcid.org/0000-0003-3108-465X
Steven K SuttonDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-2504-7601
Hyojin ChoiDepartment of Family Medicine, University of Vermont, Burlington, VT, USA.
Deanna WitteDepartment of Health Outcomes & Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Kristen J WellsMPH Department of Psychology, San Diego State University, San Diego, CA, USA.ORCID https://orcid.org/0000-0002-7359-8678
Bradley J ZebrackSchool of Social Work, University of Michigan, Ann Arbor, MI, USA.
Peter ForsythNeuro-Oncology Program, Moffitt Cancer Center, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-3756-8594
Margaret M ByrneDepartment of Health Outcomes & Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-8143-4702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We developed CARING to support neuro-oncology caregivers. CARING includes eSNAP, a web-based tool to identify social support resources, and 8 weeks of individual phone-based non-clinical navigation focused on support identification and coping skills. This study aimed to evaluate the efficacy of CARING on caregiver and patient psychosocial outcomes. Methods: We compared CARING to a waitlist control (WLC) in an RCT. Neuro-oncology patients and their caregivers were recruited from a National Cancer Institute (NCI)-designated comprehensive cancer center in Florida from February 2020 to June 2024. Eighty-one caregivers were assigned to CARING and 35 to WLC. All participants completed baseline measures, including demographics and health data. Primary outcomes collected at 8 weeks were caregiver support and self-efficacy. Secondary outcomes were caregiver burden, personal gain, and caregiver and patient anxiety and depressive symptoms. General Linear Mixed Models examined changes in outcomes from baseline to 8 weeks by condition. Results: No significant demographic differences existed between conditions. CARING caregivers reported significantly lower ratings of stress/frustration compared to feeling in control/hope ( Conclusion: CARING decreases the ratio of negative to positive emotions and perceptions of personal gain in caregivers at 8 weeks, compared to WLC.

Indexed as

brain neoplasmscaregiveroncologypsychosocial interventionrandomized controlled trial

Identifiers

PMID41798126
PMCPMC12965648

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.