Evidence map›Paper›PMID 41798069›Full record

ReviewJournal of pharmaceutical analysis2026

Antibody screening for tumor and immune hotspot targets: The frontier of new methods and technologies.

Yaping Zhou, Yitan Zou, Shaodong Lv, Dan Tan, Guangyao Li, Wenyan Fu, Changhai Lei, Mingdong Lu, Shi Hu

Abstract readReview
In one paragraph

Review in Journal of pharmaceutical analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yaping ZhouDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325003, China.
Yitan ZouDepartment of Biomedical Engineering, College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai, 200433, China.
Shaodong LvHepatic Surgery Department V, The Third Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Dan TanDepartment of Biophysics, College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai, 200433, China.
Guangyao LiDepartment of Biophysics, College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai, 200433, China.
Wenyan FuDepartment of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Changhai LeiDepartment of Biophysics, College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai, 200433, China.
Mingdong LuDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325003, China.
Shi HuDepartment of Biomedical Engineering, College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai, 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in tumor immunotherapy highlight the significant potential of antibody drugs, a key category of biological agents, for treating cancer and autoimmune diseases. This paper begins by defining and classifying key targets in tumor immunity, as well as discussing their structural and functional characteristics. Subsequently, it elaborates on innovative technologies for antibody drug screening, which, when integrated with contemporary molecular biology, biotechnology, and computational biology, have substantially enhanced the efficiency and accuracy of target identification and antibody drug screening processes. Despite the promising prospects of tumor immunotherapy, certain limitations persist in its practical implementation. In conclusion, this paper offers a comprehensive examination of the cutting-edge developments in tumor immunotherapy, focusing on the aspects of tumor immunotherapy itself, critical targets for immunotherapy, and novel technologies and methodologies for antibody screening. This analysis is crucial for advancing the field of tumor immunotherapy and for enhancing both therapeutic efficacy and safety. Furthermore, research and development (R&D) of antibody drugs in other domains, such as autoimmune and inflammatory diseases, can benefit from it.

Indexed as

Antibody drug screeningHotspot targetsInnovative technologies and methodsTarget discoveryTumor immunotherapy

Identifiers

PMID41798069
PMCPMC12962079

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.