Evidence map›Paper›PMID 41797918›Full record

ArticleiScience2026

Krüppel-like factor 10 promotes the progression of breast cancer by activating canonical NF-κB signaling.

Xue-Wei Jiang, Jing Liu, Mei-Rong Bao, Xiao-Yan Bai, Ran Tao

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xue-Wei JiangChronic Disease Research Center, Medical College, Dalian University, Dalian, Liaoning 116622, China.
Jing LiuDepartment of Humanistic Care Education and Research, School of Nursing, Dalian Medical University, Dalian, Liaoning 116044, China.
Mei-Rong BaoDepartment of Otolaryngology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, China.
Xiao-Yan BaiChronic Disease Research Center, Medical College, Dalian University, Dalian, Liaoning 116622, China.
Ran TaoChronic Disease Research Center, Medical College, Dalian University, Dalian, Liaoning 116622, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The elevation of NF-κB activity is frequently found in more malignant cancer types; however, the cause of this activation has still been controversial. Here, we showed that KLF10 promoted breast cancer progression by activating the NF-κB cascade. Mechanistically, KLF10 transcriptionally upregulated

Indexed as

Biological sciencesCancer

Identifiers

PMID41797918
PMCPMC12964234

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.