Evidence map›Paper›PMID 41797781›Full record

ArticleFrontiers in medicine2026

Fulminant amebic colitis complicated by appendiceal perforation and massive abdominal hemorrhage: a case report and literature review.

Xin Zhang, Wenxiong Li, Song Zhao, Yue Han, Wenliang Ma, Zhaoyang Jiang, Youwei Ma, Guichen Zhang, Jingyi Wang, Huimiao Jia and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xin ZhangDepartment of Critical Care Medicine, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Wenxiong LiDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Song ZhaoDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Yue HanDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Wenliang MaDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Zhaoyang JiangDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Youwei MaDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Guichen ZhangDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Jingyi WangDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Huimiao JiaDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Shuyan GuoDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Na CuiDepartment of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fulminant amebic colitis complicated by intestinal perforation or massive intra-abdominal hemorrhage is uncommon but associated with extremely high mortality. In non-endemic regions, diagnosis is frequently delayed because early manifestations resemble bacterial appendicitis or perforated peritonitis. Case presentation: We report a fatal case of Conclusion: mNGS can facilitate early recognition of severe amebiasis when conventional diagnostic modalities are uncertain, particularly in non-endemic settings. Fulminant amebic colitis complicated by perforation or hemorrhage carries a poor prognosis. Timely clinical suspicion and early anti-amebic therapy are essential to improve outcomes.

Indexed as

bowel perforationEntamoeba histolyticafulminant amebic colitisintra-abdominal hemorrhagemetagenomic next-generation sequencing

Identifiers

PMID41797781
PMCPMC12962065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.