ArticleFrontiers in medicine2026
Diagnostic accuracy of gastric filling ultrasound combined with BMI for gastroesophageal reflux disease.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to evaluate the diagnostic accuracy of gastric filling ultrasound, in combination with body mass index (BMI), for the dynamic assessment of gastroesophageal reflux in patients with gastroesophageal reflux disease (GERD)-like symptoms, using 24-h pH impedance monitoring and esophagogastroduodenoscopy (EGD) as reference standards. Methods: We enrolled 155 patients with GERD-like symptoms in our hospital. The results of gastric filling ultrasound, combined with BMI, were compared with 24-h pH impedance monitoring and EGD to assess GERD. Diagnostic accuracy was assessed using sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Cohen's kappa statistics. A calibration curve was constructed to assess agreement between the model's predicted probabilities and the observed outcomes. Decision curve analysis (DCA) was performed to evaluate clinical utility. Results: GERD patients exhibited significant differences in terms of age, BMI, His angle, and all reflux-related metrics ( Conclusion: Gastric filling ultrasound is a dynamic imaging technique that visualizes GERD symptoms. The BMI-based gastric filling ultrasound, given its good correlation with 24-h pH impedance monitoring, is a promising auxiliary diagnostic tool for GERD.
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