SynthesisFrontiers in medicine2026
Exercise prescription for axial spondyloarthritis: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Impact of Yoga on Spinal Mobility and Psychological Outcomes in Patients with Axial Spondyloarthritis: A Prospective Non-randomized Controlled Study.Rheumatology international · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic condition that significantly impacts patients' quality of life. Exercise therapy serves as a core non-pharmacological treatment modality, yet its overall efficacy and optimal prescription parameters require further clarification through high-quality evidence. This study aims to systematically evaluate the efficacy of exercise interventions for axSpA patients. Methods: Computerized searches were conducted across databases including PubMed, Embase, Web of Science, and the Cochrane Library, covering the period from inception to September 2025. Randomized controlled trials (RCTs) comparing exercise interventions with conventional treatments for axSpA were included. Two researchers independently performed literature screening, data extraction, and quality assessment. The heterogeneity of the research results was assessed using the Results: Fifteen RCTs involving 1,699 patients were included. Meta-analysis revealed that exercise intervention significantly improved disease activity in axSpA patients compared with controls (BASDAI: SMD = -0.75, 95% CI: -1.19 to -0.31; ASDAS: SMD = -0.91, 95% CI: -1.54 to -0.29), physical function (BASFI: SMD = -0.37, 95% CI: -0.47 to -0.26), spinal mobility (BASMI: SMD = -0.26, 95% CI: -0.49 to -0.04), thoracic expansion (SMD = 0.35, 95% CI: 0.04-0.65), and fatigue levels (SMD = -0.53, 95% CI: -0.78 to -0.28). Subgroup analyses indicated that different exercise modalities and intervention durations influenced treatment efficacy. Conclusion: This meta-analysis confirms that exercise interventions significantly improve core outcome measures including disease activity, physical function, spinal mobility, and fatigue in patients with axial spondyloarthritis, with statistically significant effects. The findings support the incorporation of individualized exercise prescriptions as a key component of standard axSpA treatment, providing evidence-based guidance for clinical practice. Future research should further optimize exercise prescription parameters and validate their long-term efficacy. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251144518, identifier CRD420251144518.
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