ArticleHypertension (Dallas, Tex. : 1979)2026
Stress Trajectory and Hypertension 2 to 7 Years After Delivery: A nuMoM2b-HHS Study.
Virginia R Nuckols, Bethany Barone Gibbs, Benjamin C Brewer, Allison E Gaffey, Jody L Greaney, Freda Patterson, Philip Greenland, George R Saade, William A Grobman, Lynn M Yee and 4 more
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In one paragraphArticle in Hypertension (Dallas, Tex. : 1979), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
14 authors.
Virginia R NuckolsDepartment of Kinesiology and Applied Physiology (V.R.N., M.M.W.), University of Delaware, Newark.ORCID 0000-0001-5879-5991 Bethany Barone GibbsDepartment of Epidemiology and Biostatistics, West Virginia University, Morgantown (B.B.G.).ORCID 0000-0002-0732-6148 Benjamin C BrewerCenter for Biostatistics & Health Data Science, Virginia Tech, Roanoke (B.C.B.).
Jody L GreaneyDepartment of Health Behavior and Nutrition Sciences (J.L.G., F.P.), University of Delaware, Newark.ORCID 0000-0002-9855-3978 Freda PattersonDepartment of Health Behavior and Nutrition Sciences (J.L.G., F.P.), University of Delaware, Newark.ORCID 0000-0001-6561-3092 Philip GreenlandDepartment of Preventive Medicine and Division of Cardiology (P.G.), Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0002-6327-2439 George R SaadeDepartment of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk (G.R.S.).ORCID 0000-0001-7925-5302 William A GrobmanDepartment of Obstetrics and Gynecology, Brown University, Providence, RI (W.A.G.).
Lynn M YeeDepartment of Obstetrics and Gynecology (L.M.Y.), Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0002-6274-0544 C Noel Bairey MerzBarbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (C.N.B.M.).ORCID 0000-0002-9933-5155 Judith H ChungDepartment of Obstetrics and Gynecology, University of California Irvine Health, Orange, CA (J.H.C.).
Lauren H TheilenDepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City (L.H.T.).ORCID 0000-0002-5662-6040 Megan M WennerDepartment of Kinesiology and Applied Physiology (V.R.N., M.M.W.), University of Delaware, Newark.ORCID 0000-0003-0055-783X Funding
Pregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes Supplement RequestU10HL119991 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2013 to 2018
$12.6MForebrain electroneutral transporters in salt-sensitive hypertensionR01HL163906 · NHLBI · UNIVERSITY OF DELAWARE · PI SEAN D STOCKER, Megan M Wenner · 2023 to 2026
$2.8MMechanisms of Vascular Dysfunction with Advancing Reproductive AgeR01HL146558 · NHLBI · UNIVERSITY OF DELAWARE · PI WENNER, MEGAN M · 2019 to 2023
$2.3MPregnancy as a Window for Future Cardiovascular HealthU10HL119992 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2013 to 2016
$536kPregnancy as a Window to Future Cardiovascular HealthU10HL120034 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2013 to 2016
$483kPregnancy as a Window to Future Cardiovascular HealthU10HL120018 · NHLBI · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2013 to 2016
$395kPregnancy as a Window to Future Cardiovascular HealthU10HL120006 · NHLBI · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SIMHAN, HYAGRIV N · 2013 to 2016
$218kPregnancy as a Window to Future Cardiovascular HealthU10HL119990 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI HAAS, DAVID M. · 2013 to 2016
$202kPregnancy as a Window to Future Cardiovascular HealthU10HL120019 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI WING, DEBORAH A · 2013 to 2016
$199kPregnancy as a Window to Future Cardiovascular HealthU10HL119993 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PARRY, SAMUEL I. · 2013 to 2016
$194kPregnancy as a Window to Future Cardiovascular HealthU10HL119989 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI MERCER, BRIAN M. · 2013 to 2016
$186kNHLBI NIH HHS R01 HL146558NHLBI NIH HHS R01 HL163906NHLBI NIH HHS U10 HL119989NHLBI NIH HHS U10 HL119990NHLBI NIH HHS U10 HL119991NHLBI NIH HHS U10 HL119992NHLBI NIH HHS U10 HL119993NHLBI NIH HHS U10 HL120006NHLBI NIH HHS U10 HL120018NHLBI NIH HHS U10 HL120019NHLBI NIH HHS U10 HL120034
6 · The paper itselfAbstract
backgroundAdverse pregnancy outcomes (APOs) are associated with a higher risk of developing chronic hypertension. The objectives of this study were to determine whether patterns of perceived stress during and after pregnancy were associated with blood pressure and incident hypertension 2 to 7 years after delivery, and whether having an APO modified this association.
methodsAnalyses utilized data from the prospective nuMoM2b-HHS cohort (Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Heart Health Study). Perceived stress was assessed using the Perceived Stress Scale in the first and third trimester and 2 to 7 years after delivery. Latent class trajectory analysis characterized subgroups with similar patterns of perceived stress over time. APOs were abstracted from medical charts and included hypertensive disorders of pregnancy, preterm birth, small-for-gestational-age, and stillbirth. Multivariable regression models evaluated the independent effects of perceived stress on systolic and diastolic blood pressure and incident hypertension and 2 to 7 years after delivery.
resultsThree distinct stress trajectory groups emerged, delineated by persistently low, moderate, and high stress levels. No associations between stress trajectory group and blood pressure or incident hypertension were observed after adjustment for covariates. However, there was a significant interaction between stress trajectory group and APO on blood pressure (
conclusionsThese findings suggest that elevated perceived stress may contribute to higher blood pressure, specifically among women who had an APO.
Indexed as
Blood PressureHypertensionStress, PsychologicalAdultFemaleFollow-Up StudiesHumansHypertension, Pregnancy-InducedIncidencePregnancyPregnancy OutcomeProspective StudiesRisk FactorsSubjective StressTime Factorsblood pressurehypertensionpregnancypregnancy outcomestress, psychological
Identifiers
PMID41797710
PMCPMC12974227
What OpenQuestion holds
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