Evidence map›Paper›PMID 41797436›Full record

ArticleNursing open2026

Typologies of Symptoms and Functions Among Patients With Chronic Kidney Disease and Population Characteristics: A Latent Profile Analysis.

Guoxiang Liu, Bei Yun, Xuanyi Bi, Qun Gu, Jinling Zhao, Jingting Wang

Abstract read
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Article in Nursing open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Guoxiang LiuDepartment of Nursing, The People's Liberation Army Naval Characteristic Medical Center, Shanghai, China.
Bei YunSchool of Nursing, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0006-5382-5622
Xuanyi BiSchool of Nursing, Naval Medical University, Shanghai, China.
Qun GuDepartment of Nursing, The People's Liberation Army Naval Characteristic Medical Center, Shanghai, China.
Jinling ZhaoDepartment of Nursing, The People's Liberation Army Naval Characteristic Medical Center, Shanghai, China.
Jingting WangSchool of Nursing, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-1028-177X

Funding

Soft Science Research Project of Shanghai 25692108400
6 · The paper itself

Abstract

aimsTo explore the latent classification of symptom distress and functional impairments in Chinese patients with chronic kidney disease (CKD) and analyse the influencing factors of different latent classes.

designA cross-sectional survey study.

methodsData were collected from a public tertiary hospital in Shanghai, China, between December 2023 and January 2024. Data collection was performed with the use of the Patient-Reported Outcomes Measurement Information System -29 Profile V2.1. Latent Profile Analysis and a multinomial logistic regression model were employed to identify subgroups among patients.

resultsThe results indicated three distinct subgroups of symptom distress and functional impairments among patients: Profile 1-'moderate to severe symptom distress and moderate to severe functional impairments' (29, 13.9%), Profile 2-'low symptom distress and no functional impairments' (134, 64.1%) and Profile 3-'no symptom distress and no functional impairments' (46, 22.0%). Various socio-demographic factors, such as age, payment methods, daily care by myself, anaemia, diabetes and disturbance of phosphorus metabolism, demonstrated significant associations of these factors with membership in the latent profiles (p < 0.05).

conclusionThis study identified three symptoms and functional impairment profiles in patients with CKD and the predictors of the profile membership. These findings highlight the need for personalised interventions for patients with CKD. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: Early identification of high-risk patients with CKD who experience moderate to severe symptom distress and functional impairments is crucial. Providing targeted interventions, including financial and daily care support, as well as managing comorbidities such as diabetes, anaemia and disturbances in phosphorus metabolism, is essential for achieving effective outcomes. REPORTING

methodThis study followed the STROBE statement of cross-sectional studies. PATIENT OR PUBLIC CONTRIBUTION: The study was conducted by patients, healthcare professionals, and the research team.

Indexed as

Renal Insufficiency, ChronicAdultAgedChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresSurveys and QuestionnairesSymptom Burdenchronic kidney diseasefunctional impairmentlatent profile analysispatient‐reported outcomessymptom distress

Identifiers

PMID41797436
PMCPMC12968439

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.