Evidence map›Paper›PMID 41797400›Full record

ArticleFEBS open bio2026

MiR-513a promotes human erythroid differentiation by modulating c-Jun.

MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L Eberly, Mahliya Abdurahman, T Michael Creed, Acong Yang, Taylor L Hatchet, Tristan Dyson, Shuo Gu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

MinJung KimCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-2471-189X
Brittany TaylorCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Shannon BoltenCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Christian L EberlyCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Mahliya AbdurahmanCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
T Michael CreedCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Acong YangRNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Taylor L HatchetCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Tristan DysonCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Shuo GuRNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Curt I CivinCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Tami J KingsburyCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.

Funding

THERAPEUTIC USE OF STEM CELLSP01CA070970 · NCI · JOHNS HOPKINS UNIVERSITY · PI JONES, RICHARD J · 1998 to 2012
$23.7M
MicroRNAs regulating erythroid developmentR01DK080750 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI CIVIN, CURT I · 2008 to 2010
$794k
Maryland Stem Cell Research Foundation/TEDCO 2007-MSCRFII-0114Maryland Stem Cell Research Foundation/TEDCO 2010-MSCRFII-0065-00Maryland Stem Cell Research Foundation/TEDCO 2012-MSCRFE-0272Maryland Stem Cell Research Foundation/TEDCO 2018-MSCRFD-4242NCI NIH HHS P01 CA070970NIDDK NIH HHS R01 DK080750NIH HHS P01CA070970NIH HHS R01DK080750
6 · The paper itself

Abstract

Erythropoiesis is a highly coordinated process that generates mature red blood cells from hematopoietic stem-progenitor cells (HSPCs). Erythropoietin (EPO) is a major regulator of erythropoiesis and binds to the erythropoietin receptor (EPOR), leading to increased erythroid differentiation and proliferation. MicroRNAs (miRs) are important developmental regulators, and distinct miR expression patterns are associated with specific stages of hematopoietic differentiation. Expression profiling of EPO-stimulated human HSPCs revealed increased expression of miR-513a-5p in early erythroid cells. Enforced expression of miR-513a in primary human CD34

Indexed as

Erythroid CellsErythropoiesisMicroRNAsProto-Oncogene Proteins c-junCell DifferentiationErythropoietinGATA1 Transcription FactorHematopoietic Stem CellsHumansReceptors, ErythropoietinErythropoietinGATA1 protein, humanGATA1 Transcription FactorMicroRNAsProto-Oncogene Proteins c-junReceptors, Erythropoietinc‐JUNerythroid differentiationerythropoiesisGATA1microRNAs

Identifiers

PMID41797400
PMCPMC13399029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.