ArticleBiotechnology and applied biochemistry2026
Investigation of the Medical Image Modalities to Detect the Abnormalities in the Spinal Cord Using Thresholding Techniques.
Article in Biotechnology and applied biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurately segmenting spinal structures from magnetic resonance imaging (MRI) is essential for diagnosing degenerative disc diseases. However, 1.5 T low-field MRI often suffers from high noise and low contrast, complicating the segmentation process. This study provides a systematic comparative evaluation of four thresholding-based techniques: binary/global, Otsu, adaptive, and standard deviation-based methods. Using a dataset of spinal DICOM images, we analyzed the effectiveness of these algorithms in delineating bone and soft tissue boundaries. The performance was quantitatively validated using the Dice coefficient and statistical analysis via ANOVA. Results indicate that adaptive thresholding and Otsu thresholding outperformed global methods in handling localized intensity variations, achieving a higher similarity index to expert-validated reference masks. Statistical analysis using ANOVA (p > 0.05) further suggests that while these traditional methods are computationally efficient, their efficacy is constrained by the signal-to-noise ratio (SNR) in low-field imaging. This research establishes a technical benchmark for traditional segmentation limits, highlighting the specific scenarios where a transition to deep-learning-based models becomes necessary for clinical accuracy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.