Evidence map›Paper›PMID 41797021›Full record

ArticleNuclear medicine and biology

Spatial resolution and image quality of radionuclides for PET imaging.

Sharon L Samuel, Solana Fernandez, Shelbie J Cingoranelli, Jennifer M Pyles, Jennifer L Bartels, Hailey A Houson, Yun Lu, Brian D Wright, Norio Yasui, Anna G Sorace and 1 more

Abstract read
In one paragraph

Article in Nuclear medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Immuno-positron emission tomography in cardiovascular disease: Advances, challenges, and opportunities.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sharon L SamuelDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Solana FernandezDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Shelbie J CingoranelliDepartment of Chemistry, University of Alabama at Birmingham, United States of America.
Jennifer M PylesDepartment of Chemistry, University of Alabama at Birmingham, United States of America.
Jennifer L BartelsDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Hailey A HousonDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Yun LuDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Brian D WrightDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Norio YasuiDepartment of Radiology, University of Alabama at Birmingham, United States of America.
Anna G SoraceDepartment of Radiology, University of Alabama at Birmingham, United States of America; Department of Biomedical Engineering, University of Alabama at Birmingham, United States of America. Electronic address: asorace@uabmc.edu.
Suzanne E LapiDepartment of Radiology, University of Alabama at Birmingham, United States of America; Department of Chemistry, University of Alabama at Birmingham, United States of America. Electronic address: slapi@uabmc.edu.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
UAB-UCSD O'Brien Center for Acute Kidney Injury ResearchU54DK137307 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PAUL W. SANDERS · 2023 to 2026
$4.4M
NCI NIH HHS P30 CA013148NIDDK NIH HHS U54 DK137307
6 · The paper itself

Abstract

objectiveThis study aims to characterize and compare the saturation limits, spatial resolution, and image quality of various conventional and emerging positron-emitting radionuclides using a preclinical PET/CT scanner. By characterizing the performance of these radionuclides, the study sought to provide insights into their utility in high-resolution PET imaging.

methodsRadionuclides (

resultsSaturation analysis revealed a broad range of limits across radionuclides, with

conclusionThis study demonstrates that the physical properties of radionuclides, particularly positron energy, significantly affected PET image quality, spatial resolution, and saturation thresholds. Lower-energy radionuclides like

Indexed as

Image Processing, Computer-AssistedPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadioisotopesPhantoms, ImagingSignal-To-Noise RatioRadioisotopesImage qualityImage saturationPreclinical PET radionuclidesSpatial resolution

Identifiers

PMID41797021
PMCPMC13523669

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.