Evidence map›Paper›PMID 41796413›Full record

ArticleDermatology and therapy2026

Enhanced Postablative Laser Skin Healing with a Regenerative Skincare Formulation: a Comparative Randomized Evaluator-Blinded Clinical Study.

Patricia M Brieva, Nikola Barlokova, Jyotsna Paturi, Sergej Borowik

Abstract read
In one paragraph

Article in Dermatology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Patricia M BrievaSkinCeuticals, 10 Hudson Yards, Fl 27, New York, NY, 10001, USA. patricia.brieva@loreal.com.
Nikola BarlokovaSkinCeuticals, 10 Hudson Yards, Fl 27, New York, NY, 10001, USA.
Jyotsna PaturiL'Oréal Research and Innovation, Clark, NJ, USA.
Sergej BorowikSkinCeuticals, 10 Hudson Yards, Fl 27, New York, NY, 10001, USA.ORCID http://orcid.org/0000-0003-2612-0476

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLaser resurfacing, with erbium-doped yttrium aluminum garnet (Erbium:YAG) lasers, is a leading treatment for photoaging owing to its relatively rapid healing profile. However, even with advanced technology, there remains a need for adjunctive topical treatments to enhance skin recovery, mitigate postprocedure pigmentation issues, and minimize postprocedure downtime.

methodsThis randomized, evaluator-blinded, controlled study evaluated a regenerative cream's performance following laser treatment. The study utilized a mini-zone model on the volar forearms of healthy participants to compare the cream's efficacy against laser treatment alone. Clinical and instrumental assessments were utilized to assess the efficacy of the regenerative cream in accelerating skin healing post laser.

resultsWithin 7 days of treatment, the regenerative cream significantly improved skin hydration (76%, p < 0.05) and smoothness (10%, p < 0.05), reduced skin roughness, crusting/scaling (49%, p < 0.05), and visual skin uniformity (49%, p < 0.05), compared with laser treatment alone. In addition, the regenerative cream showed greater reduction in skin redness (-27%, p < 0.05) than laser alone at day 18 post laser. Moreover, the regenerative cream outperformed an anhydrous benchmark formula in hydration, skin smoothness, and roughness after just 7 days.

conclusionsThese findings highlight the potential of the regenerative cream as a valuable addition to laser resurfacing procedures, promoting faster healing with improved aesthetic outcomes.

Indexed as

Aesthetic treatmentLasersPostprocedure recoveryRegenerative creamSkin healingTopicals

Identifiers

PMID41796413
PMCPMC13046890

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.