ArticleBMC plant biology2026
The role of RaDFR2 regulating flower color formation in Rhododendron agastum.
Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroudAs one kind of flavonoids in plants, anthocyanins are the main important pigments, which are responsible for painting flowers and fruits with various color to facilitate seed distribution and fertilization. The biosynthesis of anthocyanins is regulated by a battery of structural genes and transcription factors. However, the molecular mechanisms underlying anthocyanins accumulation in Rhododendron agastum are still unclear.
resultsHere, the transcriptome and metabolite analysis were compared to reveal candidate genes for flower color formation in R. agastum (pink colors) through RNA-Seq and HPLC-MS/MS. A total of 33 structural genes and 11 R2R3 MYBs were predicted as anthocyanins biosynthesis-related genes. Then, one critical structural gene, Dihydroflavonol 4-reductase 2 (RaDFR2), was isolated and characterized in vitro as well as in vivo to test its function on anthocyanins biosynthesis. The results showed that RaDFR2 had catalytic activity towards dihydroquercetin (DHQ) and dihydromyricetin (DHM), could restore anthocyanins biosynthesis of Arabidopsis tt3 mutant, and lead to enhanced anthocyanins accumulation in transgenic tobacco by up-regulating the expression levels of structural genes and regulatory genes.
conclusionsThis work lays the foundation for revealing the molecular mechanism of flower color formation in R. agastum, and provides genetic resources for improving outward appeal and quality of R. agastum through molecular breeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.