Evidence map›Paper›PMID 41796242›Full record

Trial reportScientific reports2026

Stretch-mediated hypertrophy and strength increases and their impact on dynamic balance performance - a randomized controlled intervention study.

Stanislav Dimitri Siegel, Mareike Sproll, Lars H Lohmann, Niklas Lebelt, Anne Marieke Fasold, Astrid Zech, Konstantin Warneke

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stanislav Dimitri SiegelInstitute of Human Movement Science and Exercise Physiology, Friedrich Schiller University Jena, Seidelstraße 20, 07749, Jena, Germany. Stanislav.siegel@uni-jena.de.
Mareike SprollInstitute of Human Movement Science, University of Hamburg, Hamburg, Germany.
Lars H LohmannInstitute of Human Movement Science and Exercise Physiology, Friedrich Schiller University Jena, Seidelstraße 20, 07749, Jena, Germany.
Niklas LebeltInstitute of Human Movement Science and Exercise Physiology, Friedrich Schiller University Jena, Seidelstraße 20, 07749, Jena, Germany.
Anne Marieke FasoldInstitute of Human Movement Science and Exercise Physiology, Friedrich Schiller University Jena, Seidelstraße 20, 07749, Jena, Germany.
Astrid ZechInstitute of Human Movement Science, University of Hamburg, Hamburg, Germany.
Konstantin WarnekeInstitute of Human Movement Science and Exercise Physiology, Friedrich Schiller University Jena, Seidelstraße 20, 07749, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimizing morphological and functional muscle parameters is of crucial importance in sports and rehabilitation. While resistance training is the most common intervention when improving muscle strength as well as general motor function such as balance, this option is not always applicable, calling for sufficient alternatives. One such opportunity is high-volume, high-intensity stretching. While previous research focused on lower leg muscles, this is the first study exploring effects on the quadriceps. Forty-nine recreationally active participants were allocated into a control group and an intervention group, which underwent twelve sessions of 15-min unilateral supervised hip flexor stretch for both legs over 4–5 weeks. Measurements included muscle thickness, isometric leg extension strength, and dynamic balance. Regional stretch-mediated ultrasound muscle thickness increased significantly in the rectus femoris (proximal: ηp²=0.24–0.41, p = 0.002-<0.001; distal: ηp²=0.14–0.40, p = 0.001-<0.001), but showed inconsistent effects in the vastus lateralis (ηp²=0.18, p = 0.008 only in the left leg). Isometric strength effects were significant in 70° (shortened position, right leg: ηp²=0.09, p = 0.04; left leg: ηp²=0.21, p = 0.001), but not at 110° (lengthened position) knee angle. Balance performance improved significantly leg-dependent in anterior (ηp²=0.13, p = 0.02, left leg), posterolateral (ηp²=0.14, p = 0.009, left leg) and posteromedial directions (ηp²=0.13, p = 0.02, right leg). This study provides first results on stretch-mediated muscle thickness and strength increases in the quadriceps with the potential for implementation in balance training, if participation in an active, supervised training program is not feasible. Future research should include additional balance outcomes, other muscle groups and clinical settings.German Clinical Trials Register ID: DRKS00036510 (03.02.2026).URL: https://drks.de/search/en/trial/DRKS00036510/details .

Indexed as

Muscle, SkeletalMuscle StrengthMuscle Stretching ExercisesPostural BalanceQuadriceps MuscleAdultFemaleHumansHypertrophyIsometric ContractionMaleResistance TrainingUltrasonographyYoung Adult

Identifiers

PMID41796242
PMCPMC12972296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.