ArticlePhysiological reports2026
Intervention effect of small extracellular vesicles derived from dental pulp stem cells on a high-altitude pulmonary edema model in male rats.
Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
High-altitude pulmonary edema (HAPE) is a life-threatening disorder caused by hypobaric hypoxia and characterized by pulmonary injury, oxidative stress, and inflammation. We investigated the effects of small extracellular vesicles derived from dental pulp stem cells (DPSCs-sEVs) in a rat model of HAPE as well as hypoxia-injured pulmonary microvascular endothelial cells (PMVECs). Rats were exposed to hypobaric hypoxia for 96 h. Lung injury was assessed by histology and immunofluorescence (VEGF, TNF-α, Occludin). Pulmonary permeability was evaluated by total protein in bronchoalveolar lavage fluid and lung homogenates and by Na
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