Effect of dynamic cerebral autoregulation of cerebral blood flow regulation during cold pressor test.

Shigehiko Ogoh, Kanoko Ito, Megumi Kaji, Narumi Kunimatsu, Kinu Tatsuta, Manabu Shibasaki

Abstract read

In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Between-visit reproducibility of cerebrovascular and cardiovascular reactivity during the cold pressor test.American journal of physiology. Heart and circulatory physiology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shigehiko OgohDepartment of Biomedical Engineering, Toyo University, Saitama, Japan.ORCID https://orcid.org/0000-0001-5297-6468

Kanoko ItoEndowed Laboratory from the Sumitomo Electric Group CSR Foundation, Nara Women's University, Nara, Japan.

Megumi KajiGraduate School of Humanities and Sciences, Nara Women's University, Nara, Japan.

Narumi KunimatsuDepartment of Biomedical Engineering, Toyo University, Saitama, Japan.

Kinu TatsutaGraduate School of Humanities and Sciences, Nara Women's University, Nara, Japan.

Manabu ShibasakiEndowed Laboratory from the Sumitomo Electric Group CSR Foundation, Nara Women's University, Nara, Japan.ORCID https://orcid.org/0000-0001-5707-2871

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 23K24727Sumitomo Electric Group CSR Foundation

6 · The paper itself

Abstract

The cold pressor test (CPT) is a clinical stress test commonly used to evoke acute pressor and respiratory responses, accompanied by increased sympathetic nerve activity. Cerebral blood flow (CBF) is well-preserved during CPT despite elevated arterial blood pressure (ABP), but the underlying mechanisms remain unclear. We hypothesized that dynamic cerebral autoregulation (dCA) contributes to this CBF preservation, preventing overperfusion under stress-induced hypertension. Thirty-seven healthy volunteers performed CPT for 3 min, while ABP, middle cerebral artery mean velocity (MCA V

Indexed as

Cerebrovascular CirculationCold TemperatureHomeostasisAdultArterial PressureBlood Flow VelocityBlood PressureCarbon DioxideFemaleHumansMaleMiddle Cerebral ArteryYoung AdultCarbon Dioxidecerebral autoregulationcold pressor reflexmiddle cerebral arteryvasoconstricton

Identifiers

PMID41795849

DOI10.14814/phy2.70813

PMCPMC12967477

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.