Evidence map›Paper›PMID 41795769›Full record

ArticleOphthalmology and therapy2026

Influence of Ocular Biometric Parameters on IOL Power Calculation Accuracy in Short and Normal Axial Length Eyes.

Yuye Zhang, Shiyu Tang, Zihan Xie, Fan Yang, Peimin Lin, Chenxi Li, Tianyu Zheng

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In one paragraph

Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuye ZhangDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Shiyu TangDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Zihan XieEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Fan YangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Peimin LinEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Chenxi LiDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Tianyu ZhengDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China. susu0102@163.com.

Funding

Association for Research in Vision and Ophthalmology BFC-KECS-LC-20251022-01National Natural Science Foundation of China 81300747Natural Science Foundation of Shanghai 19ZR1408600Natural Science Foundation of Shanghai 22ZR1410400Shanghai Municipal Human Resources Development Program for Outstanding Leaders in Medical Disciplines 2025ZZ2068The Scientific Research Program of Shanghai Pudong New Area Health Commission PW2024D-05
6 · The paper itself

Abstract

introductionThe aim of this study was to assess the effect of including lens thickness (LT) in modern intraocular lens (IOL) formulas and evaluate the influence of ocular biometric parameters on IOL power calculation accuracy in short and normal axial length (AL) eyes.

methodsThis retrospective cohort study included 174 eyes (74 short AL < 22 mm, 100 normal AL 22-24 mm). Preoperative biometry was obtained using IOLMaster 700. Predicted refractions were calculated using SRK/T, Haigis, Barrett Universal II (BUII), Kane, and Emmetropia Verifying Optical (EVO) formulas, with and without LT. Spearman correlation and multivariate regression analyses were performed to identify biometric predictors of refractive error.

resultsShort eyes had significantly shallower anterior chamber depth (ACD), smaller white-to-white (WTW), thicker LT, and higher mean keratometry (Km) and corneal astigmatism (CA) (all p < 0.01). No significant differences in mean absolute error (MAE) were detected between most formula pairs after adjustment in either subgroup. LT inclusion resulted in a less myopic mean prediction error in both subgroups (all p < 0.01), but MAE improvements were only seen in normal eyes (p < 0.05). AL and WTW were consistent predictors of absolute prediction error (APE) overall, with shorter AL and smaller WTW associated with greater APE. In short eyes, AL showed the strongest association with APE, whereas in normal eyes, WTW was most strongly correlated with APE.

conclusionsShort eyes exhibited greater biometric variability. Incorporation of LT improved the overall prediction accuracy of modern IOL formulas, particularly in normal AL eyes. AL and WTW were the most influential biometric factors affecting refractive prediction outcomes.

trial registrationChinese Clinical Trial Registry (ChiCTR), ChiCTR2600116749; retrospectively registered on 14 January 2026.

Indexed as

Intraocular lens power calculationLens thicknessOcular biometryRefractive prediction errorShort eyes

Identifiers

PMID41795769
PMCPMC13046887

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