Evidence map›Paper›PMID 41795719›Full record

ReviewClinical and experimental medicine2026

The role of macrophages and cytokines in the occurrence and development of MDS.

Peichun Li, Shuo Li, Dongmei Guan, Wenjie Xu, Jiakai Bian, Ju Deng, HongWei Wang, Fanggang Ren

Abstract readReview
In one paragraph

Review in Clinical and experimental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peichun LiShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China.
Shuo LiShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China.
Dongmei GuanShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China.
Wenjie XuShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China.
Jiakai BianShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China.
Ju DengShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China.
HongWei WangShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China. wanghw68@hotmail.com.
Fanggang RenShanxi Medical University, 56 Xinjian South Road, Taiyuan, Shanxi Province, China. burton@sxmu.edu.cn.

Funding

The Second Hospital of Shanxi Medical University Doctoral Fund Project 202201-2The Second Hospital of Shanxi Medical University Scientific and Technological Activities of Overseas Students Merit Grant 2020041The Second Hospital of Shanxi Medical University Scientific Research Grant Project for Returned Overseas Students 2021-171the Special Project of Wu Jieping Medical Foundation 320.6750.2022-8-4
6 · The paper itself

Abstract

Myelodysplastic syndrome (MDS) is a clonal hematopoietic system disease characterized by decreased blood cells, hematopoietic failure, and a higher risk of conversion to acute myeloid leukemia (AML). There are a large number of inflammatory cytokines present in the tumor microenvironment, which play different roles in different stages of tumor development. The pathogenesis of MDS is complex, persistent inflammatory signaling and cytokine dysregulation play critical roles in disease initiation, progression, and leukemic transformation.This article provides a review of the relationship between interaction between immune cells—particularly macrophages—and inflammatory cytokines in the tumor microenvironment and the occurrence and development of MDS.

Indexed as

CytokinesMacrophagesMyelodysplastic SyndromesAnimalsHumansTumor MicroenvironmentCytokinesInflammatory cytokinesMicroenvironment;macrophageMyelodysplastic syndrome

Identifiers

PMID41795719
PMCPMC12999827

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.