ArticleJournal of applied clinical medical physics2026
OVH-guided planning for superior heart and lung sparing in breast cancer radiotherapy.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
background and purposeManual planning in breast cancer radiotherapy is often time-consuming and operator-dependent, leading to inconsistencies in plan quality. This study validated an automated workflow using overlap volume histograms (OVH) to predict patient-specific dose-volume histogram (DVH) constraints, aiming to enhance cardiopulmonary sparing and planning efficiency. MATERIALS AND
methodsA historical database of 322 patients was stratified into four groups: left/right post-mastectomy radiotherapy (PMRMRT) and left/right breast-conserving radiotherapy (BCRT). Linear regression models were established to correlate OVH-derived geometric metrics (L
resultsSignificant linear correlations were observed between L
conclusionThe OVH-based framework effectively translated anatomy into achievable objectives, significantly improving heart and lung sparing for complex PMRMRT cases while streamlining clinical workflows.
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