ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026
Prospective Evaluation of Automated Right and Left Ventricular Myocardial Performance Index in Late-Onset Fetal Growth Restriction.
Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo evaluate automated right- and left-ventricular myocardial performance index (Mod-MPI) using the Samsung Hera W10 (MPI+™) system in fetuses with late-onset fetal growth restriction (FGR) and to explore its association with Doppler parameters and perinatal outcomes.
methodsThis prospective study included 177 singleton pregnancies between 32 and 39 weeks of gestation-87 with late-onset FGR and 90 gestational-age-matched controls. Fetal echocardiography and Doppler examinations were performed using the Samsung Hera W10 system with integrated MPI+™ software. Automated right and left Mod-MPI, atrioventricular valve E/A ratios, and Doppler indices were recorded. Neonatal outcomes were analyzed in relation to MPI measurements.
resultsRight-ventricular MPI and isovolumic contraction time (ICT) were significantly increased in FGR fetuses compared with controls (p = .001), whereas left-ventricular MPI showed no significant difference. Umbilical artery PI and RI were higher, and CPR and umbilical peak systolic velocity were lower in FGR. Right-sided MPI correlated negatively with gestational age, birth weight, and Apgar scores.
conclusionAutomated right-ventricular Mod-MPI provides a reproducible, objective indicator of early cardiac dysfunction in late-onset FGR. Elevation of right-sided MPI and prolongation of contraction time may reflect early myocardial adaptation preceding classical Doppler deterioration.
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