Evidence map›Paper›PMID 41795068›Full record

ArticleWorld journal of surgical oncology2026

Clinical outcomes and mechanical evaluation of patient-specific mandibular reconstruction following tumor resection: a retrospective study with finite element analysis.

Jiwon Do, Jeong Joon Han, Jong-Ho Lee, Ik-Jae Kwon

Abstract read
In one paragraph

Article in World journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiwon DoDepartment of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Daehakro 101, Jongno-gu, 03080, Seoul, Korea.
Jeong Joon HanDepartment of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Daehakro 101, Jongno-gu, 03080, Seoul, Korea.
Jong-Ho LeeOral Oncology Clinic, National Cancer Center, 10408, Ilsan, Korea.
Ik-Jae KwonDepartment of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Daehakro 101, Jongno-gu, 03080, Seoul, Korea. ijkwon@snu.ac.kr.ORCID http://orcid.org/0000-0002-8222-2971

Funding

Seoul National University No. 860-20250053
6 · The paper itself

Abstract

backgroundMandibular defects most frequently result from ablative oncologic surgery and pose major functional and esthetic challenges. While vascularized osseous free flaps remain the gold-standard treatment, patient-specific implants (PSIs) fabricated by three-dimensional (3D) printing are an increasingly popular alternative. PSIs provide superior anatomical conformity and improved cosmetic outcomes, yet their long-term mechanical reliability and fatigue resistance remain unclear. This study aimed to evaluate both the biomechanical performance and clinical outcomes of 3D-printed PSIs for mandibular reconstruction.

methodsThis retrospective study analyzed nine patients who underwent mandibular reconstruction with PSIs at Seoul National University Dental Hospital. Clinical outcomes and complications were reviewed at final follow-up (mean 36.1 ± 17.3 months; range, 5.5–63.9 months). Reconstruction plates were categorized into two types: Non-Filling Contour Plate (NFCP) and Defect-Filling Mesh Plate (DFMP). Finite element analysis (FEA) was performed on representative cases to assess stress distribution and fatigue behavior under physiological loading.

resultsDuring a mean follow-up of 36.1 months, two fractures occurred (22%): one NFCP at 34 months and one DFMP at 20 months, with both exhibiting segmental defects. FEA showed deformation of 2.01 mm in NFCP, 2.20 mm in DFMP, and 1.45 mm in modified DFMP. Peak stress was 683.3 MPa for NFCP, 378.2 MPa for DFMP and 498.8 MPa for modified DFMP, with DFMP showing mesh stress (156.6 MPa) exceeding local strength (68.2 MPa). NFCP fatigue analysis predicted ~ 184,000 cycles (≈ 3 months at maximal load), equivalent to 6–21 months under physiologic loading. Modified DFMP reduced mesh stress to 41.3 MPa.

conclusionsPSIs showed favorable clinical outcomes with excellent anatomical fit. Distinct failure mechanisms underscore the importance of fatigue life assessment, and design optimization like mesh repositioning may improve reliability for long-term use in oncologic mandibular reconstruction.

trial registrationRetrospectively registered.

Indexed as

Mandibular NeoplasmsMandibular ReconstructionAdultAgedBiomechanical PhenomenaBone PlatesFemaleFinite Element AnalysisFollow-Up StudiesHumansMaleMandibleMiddle AgedPrinting, Three-DimensionalPrognosisRetrospective Studies3D printingFinite element analysis (FEA)Mandibular reconstructionPatient-specific implants (PSIs)Plate fracture

Identifiers

PMID41795068
PMCPMC13081277

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.