ArticleJournal of gastrointestinal cancer2026
Diagnostic Performance of CT, MRI, and ERUS in Preoperative T- and N-Staging of Colorectal Cancer: A Retrospective Single-Center Analysis.
Article in Journal of gastrointestinal cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study evaluates the accuracy of computed tomography (CT), magnetic resonance imaging (MRI), and endorectal ultrasound (ERUS) in preoperative staging of colon and rectal cancers, comparing imaging results with histopathological findings. The aim is to identify strengths and limitations of each modality to optimize therapeutic strategies, particularly for neoadjuvant therapy in locally advanced cases.
methodsThis retrospective study analyzed 487 patients treated surgically for colon and rectal cancers between 2012 and 2018. Patients with incomplete imaging or histopathological data were excluded. Preoperative staging with CT, MRI, and ERUS was assessed against histopathological findings, focusing on sensitivity, specificity, and predictive accuracy (PAC). Statistical analyses were conducted to evaluate the performance of each modality for tumor (T) and nodal (N) staging, as well as risk stratification for low-risk (T1/T2) and high-risk (T3/T4) tumors.
resultsMRI showed the highest PAC for rectal cancer (89% for T-staging, 82% for N-staging), particularly for advanced tumors. CT achieved robust results for colon cancer, with PACs of 82% for T-staging and 73% for N-staging. ERUS demonstrated high accuracy for early rectal cancer, achieving an 85% PAC for low-risk tumors but performed weaker for advanced cases. MRI and CT outperformed ERUS in detecting advanced-stage tumors and nodal involvement. Risk stratification analysis confirmed MRI's superiority in rectal cancer and CT's consistency in colon cancer staging.
conclusionMRI is the modality of choice for rectal cancer staging, while CT remains the cornerstone for colon cancer staging. ERUS is best suited for early rectal tumors. These findings highlight the complementary roles of these imaging modalities and underline the need for advanced techniques to enhance diagnostic accuracy in colorectal cancer management.
Indexed as
Identifiers
41795028What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.