Evidence map›Paper›PMID 41794780›Full record

ReviewTranslational psychiatry2026

A cautionary tale for AI and machine learning in psychiatry.

Zhe Sage Chen, Katharina Schultebraucks, Wei Wu

Abstract readReview
In one paragraph

Review in Translational psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Towards AI-augmented decision making in psychiatry.Nature machine intelligence · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhe Sage ChenDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, 10016, USA. zhe.chen@nyulangone.org.ORCID http://orcid.org/0000-0002-6483-6056
Katharina SchultebraucksDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, 10016, USA.ORCID http://orcid.org/0000-0001-5085-8249
Wei WuSchool of Medicine, Shanghai Jiaotong University, Shanghai, China.ORCID http://orcid.org/0000-0003-3938-8359

Funding

National Natural Science Foundation of China (National Science Foundation of China) U24A20338U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) 157341U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) 118928U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) 129856U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) 123928U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) 056394
6 · The paper itself

Abstract

Artificial intelligence (AI) and machine learning (ML) have seen remarkable growth in mental health applications over the past few decades, demonstrating significant potential to transform psychiatric care. Despite these advancements, the translation of AI systems into clinical practice remains fraught with challenges. This Perspective examines critical hurdles in psychiatric AI research, emphasizing limitations in research rigor, model reliability, interpretability, clinical utility, and ethical considerations. We argue that a human-assisted AI framework-incorporating incremental feedback, self-adaptation, and dynamic collaboration-can address biases, enhance transparency, and build trust in AI systems. Moreover, initiatives in clinical education, cultural adaptation, and data/software sharing are essential to fostering public engagement, data transparency, and research reproducibility. By focusing on these areas, we aim to bridge the gap between AI potential and its successful, ethical implementation in mental health care, guiding the development of trustworthy, effective, and culturally adaptive AI-powered psychiatric tools.

Indexed as

Artificial IntelligenceMachine LearningMental DisordersPsychiatryHumans

Identifiers

PMID41794780
PMCPMC12979791

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.