Trial reportBMC anesthesiology2026
Analgesic efficacy of blocking nerve to vastus lateralis muscle versus lateral femoral cutaneous nerve after knee surgeries: a randomized trial.
Trial report in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06809842 (Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries: A Randomized Trial
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative pain is common following knee surgeries. Effective pain management is crucial for speeding up recovery, improving satisfaction for patients, and reducing the risk of complications. This research aimed to assess analgesic effectiveness and functional outcomes of blocking the nerve to the vastus lateralis (NVL) muscle versus the lateral femoral cutaneous nerve (LFCN).
methodsThis randomized, double-blind study was carried out on 80 patients aged ≥ 18 years, both sexes, who underwent knee surgeries under spinal anesthesia using 15 mg of bupivacaine 0.5%. Patients were allocated to two equal groups: Group VL was given the NVL block, and Group LFCN received the LFCN block. Blocks were performed at the surgical ending under ultrasound guidance with 5 ml of 0.5% bupivacaine. The primary outcome was the numerical rating score.
resultsTime of onset of sensory block and time required to achieve the maximum sensory block, pain scores at 4, 6, and 12 h postoperatively, and total morphine consumption were significantly lower, while time to the first request for rescue analgesia was significantly postponed in Group NVL compared to Group LFCN (P < 0.001). Patient satisfaction, side effects, and hospital stay lengths were similar between both groups, with no cases of respiratory depression or local anesthetic toxicity.
conclusionsThe NVL block may serve as a potential alternative to the LFCN block for postoperative analgesia in knee surgeries, as both techniques provided comparable postoperative pain control and were safe and well tolerated, while the faster sensory onset and reduced opioid consumption associated with the NVL block did not translate into a meaningful improvement in pain control. CLINICAL TRIALS REGISTRATION: Registered at clinicaltrials.gov (ID: NCT06809842, Date of registration: 30/01/2025, URL: https://clinicaltrials.gov/study/NCT06809842?cond=NCT06809842&rank=1 ).
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