Evidence map›Paper›PMID 41793956›Full record

ArticleEnvironment international2026

Racial and ethnic differences in the impact of air pollution on the risk of Alzheimer's disease and related dementias in the Multiethnic Cohort Study.

Anna H Wu, Jun Wu, Chiuchen Tseng, Burcu F Darst, Song-Yi Park, Daniel O Stram, Timothy Larson, Scott Fruin, Veronica W Setiawan, Xian Yu and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environment international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Anna H WuDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States. Electronic address: annawu@usc.edu.
Jun WuDepartment of Environmental and Occupational Health, Joe C. Wen School of Population and Public Health, University of California, Irvine CA 92697, United States.
Chiuchen TsengDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Burcu F DarstPublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.
Song-Yi ParkPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI 96813, United States.
Daniel O StramDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Timothy LarsonDepartment of Civil & Environmental Engineering and the Department of Environmental & Occupational Health Sciences, University of Washington, Seattle, WA 98109, United States.
Scott FruinDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Veronica W SetiawanDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Xian YuDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Lynne R WilkensPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI 96813, United States.
Howard HuDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Christopher HaimanDepartment of Population and Public Health Sciences, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, United States.
Beate RitzDivision of Epidemiology, University of California, Los Angeles, CA 90025, United States.
Eileen M CrimminsLeonard Davis School of Gerontology, Andrus Gerontology Center, University of Southern California, Los Angeles, CA 90089, United States.
Unhee LimPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI 96813, United States.
Iona ChengDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143, United States.
Loïc Le MarchandPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI 96813, United States.

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE · 1999 to 2026
$17.9M
Understanding Ethnic Differences in Cancer: The Multiethnic Cohort StudyUM1CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HENDERSON, BRIAN E, LE MARCHAND, LOIC · 2012 to 2014
$11.3M
EXPANDING MHAS RESEARCH INFRASTRUCTURE WITH HISTORICAL CLIMATE AND LIFETIME WORKPLACE ENVIRONMENTAL EXPOSURES INFLUENCING INEQUITIES IN AD/ADRDP30AG066589 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DANA P GOLDMAN, JULIE M ZISSIMOPOULOS · 2020 to 2026
$6.1M
NCI NIH HHS U01 CA164973NCI NIH HHS UM1 CA164973NIA NIH HHS P30 AG017265NIA NIH HHS P30 AG066589NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

BACKGROUND AND

objectivesMeta-analysis results, based largely among Whites, suggested that fine particulate matter (PM

methodsWe investigated incidence of AD (n = 4,010) and other dementia (n = 4,971) among 44,954 California Multiethnic Cohort (MEC) participants (28% African American, 14% Japanese American, 44% Latino, 14% White adults) who were enrolled in the fee-for-service component of Medicare (2001-2016). We used Cox proportional hazards regression to examine associations between exposure to PM, airport-related ultrafine particles (aUFP) and gaseous pollutants and incidence of AD, other dementia, and ADRD in a minimally- and fully-adjusted model, considering 12 established ADRD risk factors. We conducted stratified analyses to examine associations by sex, and race/ethnicity.

resultsADRD incidence was associated with PM

conclusionsIn this multiethnic population, incidence of ADRD increased with exposures to PM

Indexed as

Air PollutantsAir PollutionAlzheimer DiseaseEnvironmental ExposureHispanic or LatinoParticulate MatterRacial GroupsAgedAged, 80 and overCaliforniaCohort StudiesDementiaFemaleHawaiiHumansIncidenceAir PollutantsParticulate Matter

Identifiers

PMID41793956
PMCPMC13222114

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.