Evidence map›Paper›PMID 41793446›Full record

ArticlePsychopharmacology2026

The effect of cannabis use on the time course of positive and negative affect in the daily life of youth.

Noah N Emery, Ryan W Carpenter, Samuel Acuff, Samuel N Meisel, Angelica DeFalco, Peter D Soyster, Robert Miranda

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Article in Psychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noah N EmeryDepartment of Psychology, Colorado State University, Fort Collins, CO, USA.
Ryan W CarpenterDepartment of Psychological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Samuel AcuffRecovery Research Institute, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Samuel N MeiselDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Angelica DeFalcoDepartment of Psychology, Colorado State University, Fort Collins, CO, USA.
Peter D SoysterDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Robert MirandaCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, USA. robert_miranda_jr@brown.edu.

Funding

Biobehavioral effects of topiramate on cannabis-related outcomes in adolescentsR01DA026778 · NIDA · BROWN UNIVERSITY · PI MIRANDA, ROBERT · 2009 to 2010
$1.1M
NIDA NIH HHS DA016184NIDA NIH HHS R01 DA026778
6 · The paper itself

Abstract

rationaleContemporary theories of addiction postulate that persistent cannabis use develops in part through the positive and negative reinforcing effects on affect regulation. However, while much research has focused on affect as a stimulus for use, a dearth of research has explored acute cannabis effects on changes in affect in the natural environment.

objectivesThe present study tested the acute effects of cannabis use on positive and negative affect in daily life and explored interactions with cannabis use disorder (CUD) symptoms, among 85 youth aged 15 to 24 years (M = 19.8, SD = 2.1; 41 females, 48%) during a 1-week pre-treatment monitoring period using autoregressive multilevel models with ecological momentary assessment data (observations = 1,570).

resultsCannabis use was associated with increased positive affect and decreased negative affect after use. There was a significant quadratic lagged Positive Affect x Cannabis Use interaction, such that recent cannabis use was associated with greater positive affect specifically when previous moment positive affect was significantly lower- or higher-than-average positive affect levels. There was also a significant cross-level lagged quadratic Negative Affect x Cannabis Use x CUD severity interaction, such that recent cannabis use was associated with decreased negative affect specifically when previous moment negative affect was significantly lower- or higher-than-average negative affect levels, but most prominently among those with greater CUD symptoms.

conclusionsThe results support reinforcement models of cannabis use, suggesting that cannabis use may be both positively reinforcing generally, and negatively reinforcing for those with severe CUD.

Indexed as

Cannabis useCannabis use disorderEcological momentary assessmentNegative affectPositive affect

Identifiers

PMID41793446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.