Trial reportEuropean journal of applied physiology2026
The effects of simultaneous isometric and eccentric- or concentric-biased exercise on cardiovascular and muscular health of young individuals.
Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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13 authors.
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Abstract
purposeIsometric resistance training (IRT) and eccentric-biased training have both demonstrated improved cardiometabolic health. Consequently, simultaneous training has the potential to further enhance these improvements and overcome the commonly reported time-related barrier to exercise. Therefore, the effects of six-week simultaneous isometric and eccentric- (stair descent) or concentric-biased (stair ascent) exercise interventions were compared to a traditional isometric handgrip training protocol on cardiovascular and muscular health parameters in 54 normotensive and hypertensive young adults.
methodsParticipants (33 males, age = 21 ± 1 yr; 21 females, age = 20 ± 1 yr) were randomly assigned to four groups: simultaneous isometric exercise and stair ascent (ISO-CONC, n = 13), simultaneous isometric exercise and stair descent (ISO-ECC, n = 14), isometric handgrip (IHG) exercise (ISO, n = 13), or a passive control (CTRL, n = 14). Participants undertook thrice-weekly supervised training for six weeks, with cardiovascular and muscular function (and structure) assessed at pre- and post-training.
resultsSignificant reductions in resting systolic blood pressure (BP) were reported in all three training groups (d = 0.82–1.52), with a baseline-adjusted ANCOVA revealing that ISO-ECC diastolic BP was significantly lower than CTRL post-training. Gastrocnemius medialis muscle thickness (d = 0.79) and vastus lateralis fascicle angle only increased in ISO-CONC (r = 0.75).
conclusionsWhilst musculoskeletal improvements were only detected in the ISO-ECC group, large reductions in systolic BP were evident in all training groups, thus it may be more time-efficient to use the established isometric Handgrip intervention if reducing systolic BP is the primary therapeutic intention.
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