Evidence map›Paper›PMID 41793287›Full record

Trial reportJournal of oral rehabilitation2026

Effectiveness of a Novel Mono-Block Splint Versus a Twin-Block Splint for Anterior Disc Displacement With Reduction: A Randomised Controlled Trial.

Zhilei Liu, Antong Wu, Wenyi Cai, Jiaqian Fan, Yunyi Yuan, Yufu Lin, Rong Zhang, Qingbin Zhang, Wei Cao

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhilei LiuDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.
Antong WuDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.ORCID https://orcid.org/0000-0002-3351-3166
Wenyi CaiDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.
Jiaqian FanDivision of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, Henry Royce Institute, The University of Manchester, Manchester, UK.
Yunyi YuanGuangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.
Yufu LinDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.
Rong ZhangDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.
Qingbin ZhangDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.
Wei CaoDepartment of Temporomandibular Joint, School and Hospital of Stomatology, Guangzhou, China.ORCID https://orcid.org/0000-0001-8345-1285

Funding

Medical Science and Technology Research Foundation of Guangdong Province A2024532National Key Research and Development Program of China 2023YFC2509200Research Capability Enhancement Program of Guangzhou Medical University 2024SRP162
6 · The paper itself

Abstract

backgroundAnterior disc displacement with reduction (ADDwR) is a common subtype of temporomandibular disorders (TMD). Anterior repositioning splint (ARS) serves as a key conservative treatment modality. This study aimed to compare the clinical efficacy of a novel Mono-Block splint (nMB) with that of a Twin-Block (TB) splint in the management of ADDwR.

methodsA total of 118 patients with ADDwR were randomised to receive either an nMB or TB splint. Clinical outcomes were assessed at baseline (T0), 1 month (T1), 3 months (T3) and 6 months (T6). CBCT scans were obtained at T0 and T6, and patient satisfaction was evaluated at T6.

resultsJoint noise: The nMB group showed significantly greater improvement than the TB group at T1 and T6. Joint pain: Greater symptom relief was observed in the nMB group at the third time point (T3). MMO: The nMB splint induced a significantly greater increase in MMO only at T1. The condyle-fossa relationship: CBCT evaluation revealed comparable outcomes between the two groups, with no significant difference. Patient satisfaction: The nMB splint achieved significantly higher ratings in general satisfaction, comfort and stability, while no significant differences were noted in cleaning and retention.

conclusionThe nMB splint demonstrated superior effectiveness in reducing joint noise and improving patient comfort compared to the TB splint, while both splints exhibited similar efficacy in relieving joint pain and enhancing MMO. The nMB design offers a promising, patient-oriented approach for conservative treatment of ADDwR. Future studies will incorporate more comprehensive assessments, including MRI evaluation, and extend the follow-up period beyond 6 months to better determine the long-term therapeutic effectiveness of the nMB splint.

Indexed as

Joint DislocationsOcclusal SplintsSplintsTemporomandibular Joint DiscTemporomandibular Joint DisordersAdultCone-Beam Computed TomographyFemaleHumansMaleMiddle AgedPatient SatisfactionRange of Motion, ArticularTreatment Outcomeanterior disc displacement with reductionanterior repositioning splintCBCTtemporomandibular joint disorders

Identifiers

PMID41793287
PMCPMC13261787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.