Evidence map›Paper›PMID 41793261›Full record

ArticleVeterinary medicine and science2026

Assessment of Blood Profiles and Pain in Sport Horses Undergoing Intrarectal Ozone Therapy.

Thamirys Dias de Luna Paiva, Anna Rita de Melo Lopes, Álvaro José Chávez Silva, Maria Amélia Fernandes Figueiredo, Selene Siqueira da Cunha Nogueira, Sérgio Luiz Gama Nogueira-Filho

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Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thamirys Dias de Luna PaivaDepartamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Anna Rita de Melo LopesDepartamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Álvaro José Chávez SilvaDepartamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Maria Amélia Fernandes FigueiredoDepartamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Selene Siqueira da Cunha NogueiraDepartamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.
Sérgio Luiz Gama Nogueira-FilhoDepartamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.ORCID https://orcid.org/0000-0001-5392-0773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedical ozone is used in various treatments due to its oxidising properties.

objectiveWe aimed in this study to evaluate the impact of intrarectal ozone therapy on haematological and biochemical parameters, as well as the pain induced by the procedure in sport horses. STUDY

designIn vivo experiment with 12 Quarter Horses (3 males and 9 females) used as their own controls to assess the effects of ozone therapy.

methodsBlood samples were collected before treatment (Control), 24 h after ozone therapy (24 h post-treatment), and 7 days after the last day of ozone therapy (7 days post-treatment). These samples were analysed for haematological and biochemical parameters. Pain assessment, clinical evaluation, and the measurement of heart rate (HR) and respiratory rate (RR) were conducted before and during ozone therapy.

resultsOzone therapy significantly affected haemoglobin (F MAIN LIMITATIONS: The study's applicability is limited by the small sample size, particularly the number of males, yet the findings provide valuable insights.

conclusionsOverall, the administration of intrarectal ozone therapy over a 7-day period in horses was associated with favourable haematological modifications, which may suggest an enhancement in systemic tissue oxygenation.

Indexed as

Horse DiseasesOzonePainAnimalsFemaleHorsesMaleOzoneanti‐inflammatorycell renewalhorsesoxidative stressozonepainred blood cells

Identifiers

PMID41793261
PMCPMC12966961

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.