ArticleVeterinary medicine and science2026
Association of Haematological Parameters With TLR Genes in Healthy and Distemper-Infected Dogs Haematology and TLRs in Distemper.
Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundDetermining the expression levels of TLRs involved in innate and adaptive immunity in canine distemper infections would provide a significant advantage for controlling the disease.
objectivesThis study aimed to investigate the correlation between the expression levels of the genes toll-like receptors 1-9 (TLR1-9) and haematological parameters in healthy and distemper-infected dogs. MATERIALS AND
methodsThe study material was composed of healthy dogs (n = 8) and distemper-infected dogs (n = 8). Haematologic analyses were performed on EDTA blood samples taken from the dogs, and the expression levels of TLR1-9 genes were determined.
resultsTLR3, TLR4 and TLR9 gene expression levels significantly differed between healthy and infected dogs (p < 0.05). The comparative analysis of the haematological parameters of the two groups revealed the presence of statistically significant differences for lymphocyte count (Lymph), lymphocyte percentage (Lymph%) and granulocyte percentage (Gran%; p < 0.05). The present study demonstrated that, in the dogs infected with distemper, based on the correlation coefficients between the expression levels of TLR1-9 genes and haematological parameters, there was a positive correlation between TLR1 and PDW, TLR4 and WBC, Gran and Gran%, TLR5 and HCT, TLR6 and Gran%, TLR7 and MCV and TLR7 and PDW and a negative correlation between TLR2 and Lymph and monocyte, TLR3 and WBC and TLR5 and RDW.
conclusionsWe believe that more studies are needed to understand the effect of TLRs and haematological parameters on the course and prognosis of the distemper diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.