Evidence map›Paper›PMID 41793146›Full record

ArticleThe New phytologist2026

Arabidopsis acclimation to daily environmental fluctuations converts a defense response regulator into a susceptibility factor toward Sclerotinia.

Marie Didelon, Justine Sucher, Florent Delplace, Pedro Carvalho-Silva, Matilda Zaffuto, Adelin Barbacci, Sylvain Raffaele

Abstract read
In one paragraph

Article in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marie DidelonLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.ORCID https://orcid.org/0000-0002-8458-8117
Justine SucherLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.ORCID https://orcid.org/0000-0002-9580-1315
Florent DelplaceLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.ORCID https://orcid.org/0000-0001-9663-9332
Pedro Carvalho-SilvaLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.
Matilda ZaffutoLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.
Adelin BarbacciLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.ORCID https://orcid.org/0000-0003-3156-272X
Sylvain RaffaeleLaboratoire des Interactions Plantes-Microbes-Environnement (LIPME), Université de Toulouse, INRAE, CNRS, F-31326, Castanet-Tolosan, France.ORCID https://orcid.org/0000-0002-2442-9632

Funding

Agence Nationale de la Recherche ANR-10-LABX-41Agence Nationale de la Recherche ANR-11-IDEX-0002-02Agence Nationale de la Recherche ANR-19-CE20-15Agence Nationale de la Recherche ANR-21-CE20-10Agence Nationale de la Recherche ANR-21-CE20-30European Research Council ERC-StG-336808Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
6 · The paper itself

Abstract

Acclimation enables plants to adjust to immediate environmental fluctuations and is therefore key to the resilience of plant disease resistance in a time of climate change. Here, we report on the acclimation of Arabidopsis thaliana quantitative immune responses against the fungal pathogen Sclerotinia sclerotiorum to daily environmental fluctuations. We analyzed disease resistance phenotypes and global gene expression in plants grown in three acclimation regimes, revealing the rewiring of regulatory networks during this process. We identified pathogen-induced genes weakly sensitive to acclimation as promising bases for acclimation-proof immunity. Fluctuations in Mediterranean-like acclimation resulted in an increased disease susceptibility and the misregulation of many pathogen-responsive genes. We identified A. thaliana mutants in novel immune components contributing positively to quantitative disease resistance following temperate but not Mediterranean acclimation. Quantitative disease resistance was maintained under Mediterranean acclimation in NAC42-like mutants and associated with a switch in the repertoire of pathogen-responsive targets of this transcription factor. Our work reveals the role of immune gene networks' plasticity in acclimation and suggests new strategies to maintain plant immune function in a warming climate.

Indexed as

AcclimatizationArabidopsisAscomycotaEnvironmentPlant DiseasesArabidopsis ProteinsDisease ResistanceDisease SusceptibilityGene Expression Regulation, PlantGenes, PlantMutationPhenotypeTranscription FactorsArabidopsis ProteinsTranscription FactorsacclimationArabidopsis thalianafungal pathogenplant immunityprimingSclerotinia sclerotiorumtranscription factor

Identifiers

PMID41793146
PMCPMC13103438

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.