Trial reportJournal of biophotonics2026
LED Photobiomodulation for Pain Reduction in Temporomandibular Disorder: A Randomized, Controlled, and Blinded Clinical Trial.
Trial report in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06068959 (Effect of Photobiomodulation With LED Cluster on Pain and Mandibular and Cervical Mobility in Patients With Temporomandibular Dysfunction), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Photobiomodulation With LED Cluster on Pain and Mandibular and Cervical Mobility in Patients With Temporomandibular Dysfunction: Clinical, Randomized, Controlled and Blind Study
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
This clinical, randomized, controlled, and blinded trial evaluated photobiomodulation (PBM) using 850 nm (infrared) and 660 nm (red) LED clusters on cervical and mandibular mobility and masticatory muscles in temporomandibular disorder (TMD) patients. PBM was applied to the temporomandibular joint (TMJ) region, masseter, temporal, scalene, and trapezius muscles over six non-consecutive sessions over 2 weeks. The Research Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) were used to determine the presence of TMD. A caliper and goniometer were used to measure the mandibular and cervical range of motion, respectively. Pain was assessed with the visual analog scale (VAS) before and after intervention. Results showed pain reduction only in the LED group post-intervention; the placebo group showed no difference. No differences were observed in mouth opening, right laterality, flexion, or extension between groups, but left laterality increased in the LED group. In conclusion, PBM with LEDs effectively reduced pain in TMD patients. Trial Registration: ClinicalTrials.gov identifier: NCT06068959.
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