Evidence map›Paper›PMID 41792944›Full record

ArticleMagnetic resonance in medicine2026

Optimized Detection of Left Ventricular Hyperpolarized [1-

Fatemeh Khashami, Ivan E Dimitrov, Maximilian Fuetterer, Stefan Glöggler, Bei Zhang, Egzona Tan, Sebastian Kozerke, Anke Henning, Tarique Hussain, Craig R Malloy and 3 more

Abstract readClinical Trial, Phase I
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fatemeh KhashamiDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0009-0006-1151-8026
Ivan E DimitrovAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Maximilian FuettererInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-7456-1180
Stefan GlögglerAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-3354-6141
Bei ZhangAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-9718-1594
Egzona TanDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sebastian KozerkeInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-3725-8884
Anke HenningAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-2267-4861
Tarique HussainDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-4091-992X
Craig R MalloyDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-5077-0642
Nisha UnniDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-1549-4720
Vlad G ZahaDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-4878-891X
CTOX Trial Investigator(s)Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Funding

UT Southwestern Center for Translational MedicineUL1TR003163 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2021 to 2025
$39.3M
Cancer Prevention and Research Institute of Texas RP180404Cancer Prevention and Research Institute of Texas RR240015NCATS NIH HHS UL1 TR003163
6 · The paper itself

Abstract

purposeThis study aimed to improve the analysis of the left ventricular (LV) blood pool hyperpolarized [1-

methodsHyperpolarized [1-

resultsThe exponential numerical fitting value (0.0105 ± 0.0036) of [1-

conclusionsA mathematical model using exponential fitting and thresholding of the intensity distribution of [1-

Indexed as

Heart VentriclesMagnetic Resonance ImagingPyruvic AcidAdultAlgorithmsCarbon IsotopesFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyMaleMiddle AgedMyocardiumSignal-To-Noise RatioCarbon IsotopesPyruvic Acidcarbon‐13 magnetic resonance spectroscopygated blood pool imagingleft ventricular blood pool detectionmathematical model

Identifiers

PMID41792944
PMCPMC13156456

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.