Evidence map›Paper›PMID 41792936›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Prenatal sonographic spectrum and first-trimester diagnostic features of Ebstein anomaly: A descriptive case series.

Qing Chen, Qiumei Wu, Guorong Lyu, Huagu Tian, Zongjie Weng

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Qing ChenDepartment of Ultrasound, Fuqing City Hospital of Fujian, Fujian Medical University, Fuqing, China.
Qiumei WuDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.ORCID https://orcid.org/0000-0002-3736-7290
Guorong LyuDepartment of Medical Ultrasonud, Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.ORCID https://orcid.org/0000-0003-3123-1138
Huagu TianDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Zongjie WengDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.ORCID https://orcid.org/0000-0002-0992-9874

Funding

2023 Fujian Medical University Sailing 2023QH1203Joint Funds for the Innovation of Science and Technology 2023Y9377
6 · The paper itself

Abstract

objectiveThis descriptive case series aimed to delineate the prenatal sonographic spectrum of Ebstein anomaly (EA) across all trimesters, analyze common diagnostic pitfalls, and propose systematic imaging clues for first-trimester detection.

methodsIn this retrospective study, 40 fetuses with EA were included. A standardized echocardiographic protocol integrating transvaginal imaging for the first trimester (n = 7) and multiplanar analysis for the second and third trimesters (n = 33) was applied. Key morphological and functional parameters were documented.

resultsThe sonographic spectrum ranged from mild forms with isolated leaflet displacement to severe forms with marked cardiomegaly. In the first trimester, severe cases presented with a recognizable tetrad: (1) leftward cardiac axis deviation (>65°), (2) right atrial enlargement, (3) shortened/displaced septal leaflet with elongated anterior leaflet, and (4) severe low-origin tricuspid regurgitation. Common diagnostic challenges included isolated posterior leaflet displacement, hemodynamic confounders, and confusion with other right heart anomalies.

conclusionThis study describes the detailed prenatal sonographic spectrum of EA and proposes a structured imaging workflow. The identified first-trimester features may serve as preliminary clues for early detection of severe cases, although their diagnostic accuracy requires validation in prospective studies. These findings underscore the importance of a systematic, multiplanar examination to minimize diagnostic errors.

Indexed as

Ebstein AnomalyUltrasonography, PrenatalAdultEchocardiographyFemaleGestational AgeHumansPregnancyPregnancy Trimester, FirstRetrospective StudiesEbstein anomalyfetal echocardiographyfirst‐trimester diagnosismisdiagnosis and missed diagnosisprenatal diagnosis

Identifiers

PMID41792936
PMCPMC13377310

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